Peptides
Protease-Activated Receptor-1, PAR-1 Agonist 2, amide - 1 mg
€100.00
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- Cat.Number : AS-62936
- Manufacturer Ref. :
-
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In stock
This peptide is a thrombin receptor activating peptide. This PAR-1 agonist peptide reversibly binds to PAR-1 mimicking the 'tethered ligand' that thrombin makes available through proteolytic cleavage of substrate. It is also known to cause increase in liquid and protein permeability much like thrombin.
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Citations
Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46
Blood . 2012 Nov 13 ; 120(26) 5237 | DOI : 10.1182/blood-2012-08-452169
- LO. Mosnier
- et al