Peptides
T20, Enfuvirtide - 1 mg
€445.00
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- Cat.Number : AS-61235
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This 36-residue synthetic peptide strongly inhibits HIV-1 viral fusion with CD4 cells with an EC50 of 1 ng/ml.
It is a peptide mimetic of an essential region within the viral envelope glycoprotein gp41 that functions by blocking gp41 structural rearrangements at a transitional pre-fusion conformation.
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Citations
Phosphorylation of HIV Nef by cAMP-dependent protein kinase
Virology. . 2005 Jan 20 ; 331(2) 367 | DOI : 10.1016/j.virol.2004.11.004
- PL. Lia
- et al