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3' DABCYL Molecular Beacons

Molecular Beacons

Eurogentec is a licensed supplier of Molecular Beacons, and offers a large number of fluorescent reporters and quenchers. All Molecular Beacons are provided double-HPLC purified. The length of Molecular Beacons with a 3’ DABCYL should be comprised between 25 to 45 bases.


DescriptionSize Reference USD  
M Beacon 5' TAMRA + 3 'DABCYL 40 nmol scale - 1 probe1 probe PB-MB200-004 336.00Configure...
M Beacon 5' TAMRA + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB200-020 408.00Configure...
M Beacon 5' TAMRA + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB200-100 480.00Configure...
M Beacon 5' FAM + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB201-004 312.00Configure...
M Beacon 5' FAM + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB201-020 336.00Configure...
M Beacon 5' FAM + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB201-100 432.00Configure...
M Beacon 5' FAM + 3' DABCYL 2.5 µmol scale - 1 probe1 probe PB-MB201-M02 714.00Configure...
M Beacon 5' FAM + 3' DABCYL 5 µmol scale - 1 probe1 probe PB-MB201-M05 1 116.00Configure...
M Beacon 5' FAM + 3' DABCYL 10 µmol scale - 1 probe1 probe PB-MB201-M10 1 837.00Configure...
M Beacon 5' HEX + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB210-004 312.00Configure...
M Beacon 5' HEX + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB210-020 384.00Configure...
M Beacon 5' HEX + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB210-100 432.00Configure...
M Beacon 5' TET + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB212-004 336.00Configure...
M Beacon 5' TET + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB212-020 408.00Configure...
M Beacon 5' TET + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB212-100 480.00Configure...
M Beacon 5' JOE + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB214-004 336.00Configure...
M Beacon 5' JOE + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB214-020 408.00Configure...
M Beacon 5' JOE + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB214-100 480.00Configure...
M Beacon 5' ROX + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB216-004 336.00Configure...
M Beacon 5' ROX + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB216-020 408.00Configure...
M Beacon 5' ROX + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB216-100 480.00Configure...
M Beacon 5' ROX + 3' DABCYL 2.5 µmol scale - 1 probe1 probe PB-MB216-M02 900.00Configure...
M Beacon 5' ROX + 3' DABCYL 5 µmol scale - 1 probe1 probe PB-MB216-M05 1 477.00Configure...
M Beacon 5' ROX + 3' DABCYL 10 µmol scale - 1 probe1 probe PB-MB216-M10 2 317.00Configure...
M Beacon 5' Rhodamine-6G + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB220-004 336.00Configure...
M Beacon 5' Rhodamine-6G + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB220-020 408.00Configure...
M Beacon 5' Rhodamine-6G + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB220-100 480.00Configure...
M Beacon 5' Texas Red® + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB230-004 336.00Configure...
M Beacon 5' Texas Red® + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB230-020 408.00Configure...
M Beacon 5' Texas Red® + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB230-100 480.00Configure...
M Beacon 5' Yakima Yellow® + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB240-004 336.00Configure...
M Beacon 5' Yakima Yellow® + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB240-020 408.00Configure...
M Beacon 5' Yakima Yellow® + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB240-100 480.00Configure...
M Beacon 5' Dragonfly Orange™ + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB245-004 336.00Configure...
M Beacon 5' Dragonfly Orange™ + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB245-020 408.00Configure...
M Beacon 5' Dragonfly Orange™ + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB245-100 480.00Configure...
M Beacon 5' Cy® 3 + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB250-004 330.00Configure...
M Beacon 5' Cy® 3 + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB250-020 402.00Configure...
M Beacon 5' Cy® 3 + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB250-100 468.00Configure...
M Beacon 5' Cy5® + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB255-004 324.00Configure...
M Beacon 5' Cy5® + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB255-020 396.00Configure...
M Beacon 5' Cy5® + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB255-100 456.00Configure...
M Beacon 5' Cy5® + 3' DABCYL 2.5 µmol scale - 1 probe1 probe PB-MB255-M02 858.00Configure...
M Beacon 5' Cy5® + 3' DABCYL 5 µmol scale - 1 probe1 probe PB-MB255-M05 1 405.00Configure...
M Beacon 5' Cy5® + 3' DABCYL 10 µmol scale - 1 probe1 probe PB-MB255-M10 2 203.00Configure...
M Beacon 5' Alexa® + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB260-004 336.00Configure...
M Beacon 5' Alexa® + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB260-020 408.00Configure...
M Beacon 5' Alexa® + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB260-100 480.00Configure...
M Beacon 5' Cascade Blue® + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB270-004 336.00Configure...
M Beacon 5' Cascade Blue® + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB270-020 408.00Configure...
M Beacon 5' Cascade Blue® + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB270-100 480.00Configure...
M Beacon 5' DYOMICS + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB280-004 On RequestConfigure...
M Beacon 5' DYOMICS + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB280-020 On RequestConfigure...
M Beacon 5' DYOMICS + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB280-100 On RequestConfigure...
M Beacon 5' BODIPY® + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB285-004 336.00Configure...
M Beacon 5' BODIPY® + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB285-020 408.00Configure...
M Beacon 5' BODIPY® + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB285-100 480.00Configure...
M Beacon 5' ATTO + 3' DABCYL 40 nmol scale - 1 probe1 probe PB-MB290-004 336.00Configure...
M Beacon 5' ATTO + 3' DABCYL 200 nmol scale - 1 probe1 probe PB-MB290-020 408.00Configure...
M Beacon 5' ATTO + 3' DABCYL 1000 nmol scale - 1 probe1 probe PB-MB290-100 480.00Configure...
* More info on the Purifications page

More info

Molecular Beacons are probes which contain a stem-loop structure, a fluorophore and a quencher at their 5’ and 3’ ends, respectively.

The ‘stem’ sequence keeps the fluorophore and the quencher together, but only in the absence of a sequence complementary to the ‘loop’ sequence. As long as the fluorophore and the quencher are in close vicinity, any photons emitted by the fluorophore are absorbed by the quencher. This phenomenon is called collisional (or proximal) quenching.

In the presence of a complementary sequence, the probe unfolds and hybridizes to the target, the fluorophore is displaced from the quencher, which can no longer absorb the photons emitted by the fluorophore, and the probe starts to fluoresce. The amount of signal is proportional to the amount of target sequence, and is measured in Real-Time to allow quantification of the amount of target sequence.

Eurogentec is a licensed supplier of Molecular Beacons, and offers a large number of fluorescent reporters and quenchers. All Molecular Beacons are provided double-HPLC purified and controlled by analytical HPLC and MALDI-TOF MS. The maximum length of standard Molecular Beacons with a 3’ DABCYL is 45 bases. Molecular Beacons are provided lyophilized in individual tubes.

Eurogentec determines upon request the signal-to-noise ratio (STNR) for each Molecular Beacons by hybridizing it to its complementary sequence and comparing fluorescence to background. For FAM labelled Molecular Beacons, the STNR should be > 15. All other dyes require a signal-to-noise ratio > 10. Eurogentec proposes two specialty products: Wavelength-Shifting Molecular Beacons and 2’ O-Methyl RNA Molecular Beacons.

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