Alpha-Synuclein ELISA Kit

α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson’s disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly produced in brain: specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express the α-Synuclein gene at very low levels. The physiological role of α-Synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.

The SensoLyte® α-Synuclein Quantitative ELISA Kit (Human/Rat) provides a convenient and quantitative assay for determining α-Synuclein amount in cell and tissue lysate as well as in body fluids. This kit is optimized to detect human or rat α-Synuclein in cell and tissue lysate, and in body fluids such as cerebrospinal fluid (CSF), plasma, and serum. Wells are pre-coated with anti-α-Synuclein monoclonal antibodies, blocked, and stabilized for long-term storage. The amount of α-Synuclein is quantified using sandwich ELISA: rabbit polyclonal anti-α-Synuclein specific antibodies directly conjugated to horseradish peroxidase (HRP) are used to detect captured α-Synuclein, and are added simultaneously with samples and standards during the assay. This eliminates extra incubation and washing steps and makes this kit one-step procedure for α-Synuclein quantification.

Description	Size	Reference		USD	Qty
SensoLyte® Anti-a-Synuclein (Human) ELISA Kit - 1 kit	1 kit	AS-55550-H		520.00		Add to cart