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Anti-MOG IgG Quantitative ELISA Kits

iD Sensolyte® Assay Kits

Myelin oligodendrocyte glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system myelin. MOG (1-125) is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to MOG (1-125) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in various animals. However, the exact pathological role and action of anti-human MOG (1-125) autoantibody is not known and is currently under vigorous investigation. 

MOG peptide fragment (35-55) induces autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to MOG (35-55) is present in multiple sclerosis (MS) patients and MOG (35-55)-induced experimental autoimmune encephalomyelitis (EAE) mice. 

The SensoLyte® Anti-MOG (35-55) IgG Quantitative ELISA Kit (mouse/rat) provides a convenient, quantitative assay for detecting anti-MOG (35-55) IgG. This colorimetric assay, useful for determining the amount of anti-MOG (35-55) IgG present, can help provide information on the role anti-MOG (35-55) IgG plays in the development of EAE, an in vivo animal model for MS pathogenesis. The assays are performed in a convenient 96-well (strips format). 

The SensoLyte™ Anti-MOG (1-125) IgG Quantitative ELISA Kits (Human, Mouse or Rat) provide a convenient quantitative assay for anti-MOG (1-125) autoantibody (human, mouse or rat). These kits are useful to researchers for determining the amount of anti-MOG (1-125) antibody present, and can help provide information on the role it plays in the development and treatment of multiple sclerosis and for EAE, an animal model for multiple sclerosis pathogenesis.

DescriptionSize Reference USD Qty  
SensoLyte Anti hMOG Human IgG Elisa1 kit AS-55153-H 526.00Add to cart
SensoLyte Anti hMOG Mouse IgG Elisa1 kit AS-55153-M 457.00Add to cart
SensoLyte® Anti-MOG(35-55) IgG Quantitative ELISA Kit (mouse/rat) *Colorimetric* - 1 kit1 kit AS-54465 457.00Add to cart
SensoLyte® Anti-Mouse MOG (1-125) IgG Quantitative ELISA Kit *Colorimetric* - 1 kit1 kit AS-55156 457.00Add to cart
SensoLyte® Anti-Rat MOG (1-125) IgG Quantitative ELISA Kit *Colorimetric* - 1 kit1 kit AS-55157 457.00Add to cart


Benefits



• Convenient Format: - Pre-coated and pre-blocked 96-well strip plate
- Ready-to-use substrate solutions and other assay components
• Minimal Sample Size: - Requires only 0.5-1 μl of serum or cerebrospinal fluid to perform the assay
• High Sensitivity: - Detects as low as 1 ng/ml anti-human MOG (1-125) IgG
- Detects as little as 50 pg anti-MOG
(35-55) IgG subtypes
• Broad Dynamic Range: - Detection of 0.5 to 500 ng antibody/ml serum
(depending on the kit and the colorimetric developing time)


Description

λ
Ex/Em
(nm)
Biological sample volume Lowest Detection Limit  Kit contains Assay time # of
assays in
96-well plate
MOG (Myelin Oligodendrocyte Glycoprotein) Assay Kit
SensoLyte® Anti-Rat MOG (1-125) Assay 
Colorimetric
450 8-500 ng/ml 1 ng/ml • Rat-MOG (1-125) coated and BSA blocked 8-well strips (12 strips)
• Anti-Rat MOG (1-125) IgG standard
• 1X Sample Dilution Buffer
• 10X Wash Buffer
• TMB color substrate solution
• Stop Solution
• Secondary antibody, Goat anti-Rat IgG-HRP
2-3 hours 1x 96 well plate
(80 assays)
SensoLyte® Anti-Human MOG (1-125) Assay
Colorimetric
450 8-500 ng/ml 1 ng/ml • Human-MOG (1-125) coated and BSA blocked 8-well strips (12 strips)
• Human Anti-Human IgG standard
• 1X Sample Dilution Buffer
• 10X Wash Buffer
• TMB color substrate solution
• Stop Solution
• Secondary antibody: Goat anti-Human IgG-HRP
2-3 hours 1x 96 well plate
(80 assays)
SensoLyte® Anti-Mouse MOG (1-125) Assay
Colorimetric
450 8-500 ng/ml 1 ng/ml • Mouse-MOG (1-125) coated and BSA blocked 8-well strips (12 strips)
• Anti-Mouse MOG (1-125) IgG standard
• 1X Sample Dilution Buffer
• 10X Wash Buffer
• TMB color substrate solution
• Stop Solution
• Secondary antibody, Goat anti-Mouse IgG-HRP
2-3 hours 1x 96 well plate
(80 assays)
SensoLyte®
Anti - MOG (35 - 55) IgG Quantitative ELISA Kit (mouse/rat)
Colorimetric
450 8-500 ng/ml 100 pg • MOG (35-55) coated and BSA blocked 8-well strips (12 strips)
• Mouse Anti-MOG (35-55) IgG standard
• 1X Sample Dilution Buffer
• 10X Wash Buffer
• TMB color substrate solution
• Stop Solution
• Secondary antibody, Goat anti-Mouse IgG-HRP
• Secondary antibody, Goat anti-Rat IgG-HRP
• Rat anti-MOG (35-55) IgG standard
2-3 hours 1x 96 well plate
(80 assays)
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