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Ghrelins and Obestatins Peptides

Catalog Go™ peptides

Ghrelin is a 28-amino-acid peptide hormone produced by the stomach in mammals. The major active form of Ghrelin is a peptide with an n-octanoyl modification at Ser3 (n-octanoyl Ghrelin). Endogenous Ghrelin participates in the regulation of food intake and body weight. The secretion of ghrelin is augmented under conditions of both gastric emptying and filling, and the release is stimulated by intestinal hormones. Ghrelin is also involved in the release of growth hormone from the anterior pituitary through activation of the growth hormone secretagogue receptor (GHS-R). It is also a potent vasodilator that can be detected in endothelial cells of arteries and veins in human. 

Derived from the ghrelin gene, obestatin peptide suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain. Obestatin was thought to bind to the orphan G protein–coupled receptor GPR39; however new data confirm that I125-obestatin does not bind GPR39.

DescriptionSize Reference USD Qty  
[Des-octanoyl]-Ghrelin, human - 1 mg1 mg AS-61177 220.00Add to cart
[Des-octanoyl]-Ghrelin, rat, mouse - 1 mg1 mg AS-60981 220.00Add to cart
Ghrelin, human - 1 mg1 mg AS-24157 242.00Add to cart
Ghrelin, human - 5 mg5 mg AS-24158 968.00Add to cart
Ghrelin, human, Biotin-labeled - 1 mg1 mg AS-29391 363.00Add to cart
Ghrelin, rat, mouse - 1 mg1 mg AS-24159 242.00Add to cart
Ghrelin, rat, mouse - 5 mg5 mg AS-24160 968.00Add to cart
Reference Name Sequence MW (Da)
AS-62931 [Ala1, D-Trp2,4, Leu6]-Ghrelin Receptor Agonist AwFwLL 835
AS-62930 [D-Trp1,3, Leu5]-Ghrelin Core-Ligand wFwLL 763,9
AS-61177 [Des-octanoyl]-Ghrelin, human GSSFLSPEHQRVQQRKESKKPPAKLQPR 3244,7
AS-60981 [Des-octanoyl]-Ghrelin, rat GSSFLSPEHQKAQQRKESKKPPAKLQPR 3188,7
AS-61714 Biotin-Ghrelin, bovine Biotin-GS-S(n-octanoylated)-FLSPEHQKLQRKEAKKPSGRLKPR 3442,8
AS-29391/29392 Biotin-Ghrelin, human Biotin-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR 3597,2
AS-61905 C-terminal Proghrelin Isoform Peptide, mouse RRQLTSNHGQA 1267,4
AS-62358 Ghrelin (1-18) GS-S(n-octanoyl)-FLSPEHQRVQQRKES 2227,5
AS-60870 Ghrelin, bovine GS-S(n-octanoylated)-FLSPEHQKLQRKEAKKPSGRLKPR 3216,8
AS-24157/24158 Ghrelin, human GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR 3370,9
AS-29396/29397 Ghrelin, human, FAM-labeled FAM-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR 3729,2
AS-29387/29388 Ghrelin, human, TAMRA-labeled TAMRA-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR 3783,4
AS-24159/24160 Ghrelin, rat GS-S(n-octanoyl)-FLSPEHQKAQQRKESKKPPAKLQPR 3314,8
AS-62041 Obestatin (11-23), human LSGVQYQQHSQAL 1458,6
AS-62040 Obestatin (11-23), rat, mouse LSGAQYQQHGRAL 1428,6
AS-61434 Obestatin, human FNAPFDVGIKLSGVQYQQHSQAL-NH2 2547,9
AS-61435 Obestatin, rat, mouse FNAPFDVGIKLSGAQYQQHGRAL-NH2 2517,9
Reference Name Description
AS-62931 [Ala1, D-Trp2,4, Leu6]-Ghrelin Receptor Agonist This peptide is a high potency agonist of the ghrelin receptor.
AS-62930 [D-Trp1,3, Leu5]-Ghrelin Core-Ligand This peptide is an active core-ligand which affects ghrelin receptor with a characteristic low biphasic dose-response curve. At low concentrations, it acts as a partial agonist; at high concentrations as a partial inverse agonist. The aromatic wFw tripeptide is suggested to represent the essential binding unit in the inverse agonists for ghrelin receptors.
AS-61177 [Des-octanoyl]-Ghrelin, human  
AS-60981 [Des-octanoyl]-Ghrelin, rat  
AS-61714 Biotin-Ghrelin, bovine The octanoyl modification at Ser3 (n-octanoyl Ghrelin) is the major active form of ghrelin.
AS-29391/29392 Biotin-Ghrelin, human  
AS-61905 C-terminal Proghrelin Isoform Peptide, mouse This is a unique C-terminal peptide encoded by the exon 4 - deleted proghrelin variant. This mouse proghrelin isoform with the complete deletion of exon 4 is potentially generated by alternative splicing of the mouse ghrelin gene. This C-terminal peptide proghrelin isoform is widely expressed in the multiple mouse tissues.
AS-62358 Ghrelin (1-18) This peptide is amino acids 1 to 18 fragment of ghrelin. Ghrelin is a potent agonist at the human growth hormone secretagogue receptor 1a (hGHSR1a). The entire sequence of ghrelin is not necessary for its activity.
AS-60870 Ghrelin, bovine  
AS-24157/24158 Ghrelin, human This peptide of 28 amino acids, in which Ser3 is n-octanoylated, is an endogenous ligand specific for growth hormone secretagogue receptor (GHS-R).
AS-29396/29397 Ghrelin, human, FAM-labeled This is a fluorescent (FAM)-labeled Ghrelin peptide, Abs/Em=494/521 nm.
AS-29387/29388 Ghrelin, human, TAMRA-labeled This is a fluorescent (TAMRA)-labeled Ghrelin peptide, Abs/Em=541/565 nm.
AS-24159/24160 Ghrelin, rat Endogenous growth-hormone releasing peptide with novel regulatory mechanism.
AS-62041 Obestatin (11-23), human  
AS-62040 Obestatin (11-23), rat, mouse  
AS-61434 Obestatin, human Derived from the ghrelin gene, this peptide has the opposite effects of Ghrelin. It suppresses food intake; inhibits jejunal contraction and decreases body weight. For research use only. 
AS-61435 Obestatin, rat, mouse Derived from the ghrelin gene, this peptide has the opposite effects of Ghrelin. It suppresses food intake; inhibits jejunal contraction and decreases body weight. For research use only. 

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