Select your products and services :
Select your country :
Asia and South Pacific
Middle East and Africa

Update your choices | BU : Life Science | Country : USA

OptimAb™ Anti-5-Methylcytosine Antibody

OptimAb catalog antibodies

Clone 33D3 recognizes the modified base 5-methylcytosine (5-MeCyt) found in plant and vertebrate DNA. It specifically distinguishes 5-MeCyt from its normal DNA base counterpart, cytosine, making it an ideal tool for gene promoter methylation analysis. DNA methylation is a postreplication process involved in the establishment of genomic imprinting, in the control of gene expression and of differentiation. Carcinogenesis is associated with alterations of the DNA methylation pattern: a global DNA hypomethylation is often detected in tumor tissues, associated with local hypermethylation sites. This antibody has been developed to discriminate between the modified base and its normal counterpart. lt has been used to detect alterations in the urinary excretion of nucleosides by cancer patients, to visualize the distribution of methyl-rich regions along human chromosomes, to quantify in situ differences between normal and malignant cells from peripheral blood as well as on tissue sections. The antibody is ideal for the histopathological analysis of tissue samples without employing DNA extraction procedures that destroy cells.

DescriptionSize Reference USD Qty  
OptimAb Anti-5-Methylcytosine (33D3) - 0.1 mg0.1 mg BI-MECY-0100 488.00Add to cart
OptimAb Anti-5-Methylcytosine (33D3) - 0.5 mg0.5 mg BI-MECY-0500 1 708.00Add to cart
OptimAb Anti-5-Methylcytosine (33D3) - 1 mg1 mg BI-MECY-1000 2 442.00Add to cart

Intented use

Research use only; not to be administered to humans or used for medical diagnostics

The EGT Ordering System (EOS) is the simplest and easiest way to place your orders including:

All oligonucleotides
All Kits & Reagents (including Catalogue Antibodies & Peptides, Real-Time qPCR Mixes, Taq Polymerases, Sensolyte® Assays...)

Please use your Login or Register Now to directly access your customized EOS interface.

You can still place orders by:
  When placing your order, please include the following information:
  Contact person purchase order number
  delivery address product description and reference number
  invoice address quotation number
  telephone number  

We use cookies to ensure the best experience on our website. By continuing to use this website, you consent to our cookie policy.