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OptimAb™ Anti-beta-Amyloid Antibody

OptimAb™ catalog antibodies

Beta-Amyloid forms are deposited in the CNS of patients with Alzheimer’s disease and Down’s syndrome. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Beta-Amyloid (1-42) is the principal species associated with senile plaque amyloids, while Beta-Amyloid (1-40) is more abundant in cerebrovascular amyloid deposits. Both result from the cleavage of Amyloid Precursor Protein (APP) by secretases. The mAb 6E10 reacts to the abnormally processed isoforms, as well as precursor forms. The mAb 4G8 reacts to the abnormally processed isoforms, as well as precursor forms. The mAb 12F4 reacts with the C-terminus of Beta-Amyloid and is specific to the isoform ending at the 42nd residue. SIG-39138 anti-sAPPß pAb is specific for the soluble fragment of APP, cleaved N-terminus to the beta-secretase cleavage site. It has negligible cross reactivity to sAPPα or full length APP.



DescriptionSize Reference USD Qty  
OptimAb Beta Amyloid 1-16 (6E10) Monoclonal Antibody, HRP Labeled100 µg SIG-39345-050 413.00Add to cart
OptimAb Beta Amyloid 17-24 (4G8) Monoclonal Antibody, HRP Labeled100 µl SIG-39245-100 413.00Add to cart
OptimAb Beta-Amyloid 1-16 (6E10) Monoclonal Antibody, Biotin Labeled100 µg SIG-39340-100 401.00Add to cart
OptimAb Beta-Amyloid 1-16 (6E10) Monoclonal Antibody, purified100 µg SIG-39320-100 343.00Add to cart
OptimAb Beta-Amyloid 1-16 (6E10) Monoclonal Antibody, purified500 µg SIG-39320-500 1 035.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, Biotin Labeled50 µg SIG-39144-050 378.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, HRP Labeled50 µg SIG-39147-050 401.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, purified50 µg SIG-39142-050 331.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, purified250 µg SIG-39142-250 977.00Add to cart
OptimAb Beta-Amyloid 17-24 (4G8) Monoclonal Antibody, Biotin Labeled100 µg SIG-39240-100 401.00Add to cart
OptimAb Beta-Amyloid 17-24 (4G8) Monoclonal Antibody, purified100 µg SIG-39220-100 343.00Add to cart
OptimAb Beta-Amyloid 17-24 (4G8) Monoclonal Antibody, purified500 µg SIG-39220-500 1 035.00Add to cart
OptimAb sAPPbeta Polyclonal Antibody, purified50 µg SIG-39138-050 628.00Add to cart


Intented use

Research use only; not to be administered to humans or used for medical diagnostics

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