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OptimAb™ Anti-beta-Amyloid Antibody

OptimAb™ catalog antibodies

Beta-Amyloid forms are deposited in the CNS of patients with Alzheimer’s disease and Down’s syndrome. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Beta-Amyloid (1-42) is the principal species associated with senile plaque amyloids, while Beta-Amyloid (1-40) is more abundant in cerebrovascular amyloid deposits. Both result from the cleavage of Amyloid Precursor Protein (APP) by secretases. The mAb 6E10 reacts to the abnormally processed isoforms, as well as precursor forms. The mAb 4G8 reacts to the abnormally processed isoforms, as well as precursor forms. The mAb 12F4 reacts with the C-terminus of Beta-Amyloid and is specific to the isoform ending at the 42nd residue. SIG-39138 anti-sAPPß pAb is specific for the soluble fragment of APP, cleaved N-terminus to the beta-secretase cleavage site. It has negligible cross reactivity to sAPPα or full length APP.



DescriptionSize Reference USD Qty  
OptimAb Beta-Amyloid 1-16 (6E10) Monoclonal Antibody, Biotin Labeled - 100 µg100 µg SIG-39340-100 422.00Add to cart
OptimAb Beta-Amyloid 1-16 (6E10) Monoclonal Antibody, purified - 100 µg100 µg SIG-39320-100 361.00Add to cart
OptimAb Beta-Amyloid 1-16 (6E10) Monoclonal Antibody, purified - 500 µg500 µg SIG-39320-500 1 090.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, Biotin Labeled - 50 µg50 µg SIG-39144-050 398.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, purified - 250 µg250 µg SIG-39142-250 1 028.00Add to cart
OptimAb Beta-Amyloid 1-42 (12F4) Monoclonal Antibody, purified - 50 µg50 µg SIG-39142-050 349.00Add to cart
OptimAb Beta-Amyloid 17-24 (4G8) Monoclonal Antibody, Biotin Labeled - 100 µg100 µg SIG-39240-100 422.00Add to cart
OptimAb Beta-Amyloid 17-24 (4G8) Monoclonal Antibody, purified - 100 µg100 µg SIG-39220-100 361.00Add to cart
OptimAb Beta-Amyloid 17-24 (4G8) Monoclonal Antibody, purified - 500 µg500 µg SIG-39220-500 1 090.00Add to cart
OptimAb sAPPbeta Polyclonal Antibody, purified - 50 µg50 µg SIG-39138-050 661.00Add to cart


Intented use

Research use only; not to be administered to humans or used for medical diagnostics

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